Powerful New Diabetes Pill Cuts Weight and Lowers Blood Sugar

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Experimental oral GLP-1 pill shows strong Phase 2b results in diabetes and obesity trials

The New Pill Is Called Elecoglipron

The Diabetes Trial Included 404 Adults

Blood Sugar Fell by Up to 1.9 Percentage Points

Most Reached the Standard Diabetes Target

Participants Also Lost 7.7% of Their Weight

A Separate Obesity Trial Produced Greater Losses

It Can Be Taken Without Fasting

Gastrointestinal Effects Were Common

It Works Through the GLP-1 Pathway

Larger Trials Must Confirm the Findings

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A once-daily experimental pill has delivered strong results for adults with type 2 diabetes, substantially lowering long-term blood sugar while also producing meaningful weight loss. The medicine, called elecoglipron, was tested in the Phase 2b SOLSTICE trial across nine countries.

The findings were published in The Lancet and presented at the American Diabetes Association’s 2026 Scientific Sessions. Elecoglipron is not yet approved for routine use, but AstraZeneca is now advancing it into a larger Phase 3 programme.

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